What does Ayy LMAO mean?
Ayy Lmao
Ayy LMAO is a popular internet meme
“Ayy LMAO” is an internet meme which has recently become popular. It has been around since late 2012, and has become increasingly popular in mid-to-late 2013, according to knowyourmeme.com. It originated as the photo above — an alien with the plain “ayylmao” text overtop of it. Soon enough, more photos of aliens emerged with the text. #ayylmao has become very popular on social networking sites like Tumblr, Facebook, Twitter, and Instagram, as well as other places like Reddit.

See other slang & acronym definitions on whatdoesctfumean.com:
THOT – MCM – WCW – TBT – IANAL – OOTD